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Gene: Pfkm (phosphofructokinase, muscle) Rattus norvegicus
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Symbol: Pfkm
Name: phosphofructokinase, muscle
Description: Exhibits 6-phosphofructokinase activity; anion binding activity; and carbohydrate binding activity. Involved in several processes, including fructose 1,6-bisphosphate metabolic process; fructose 6-phosphate metabolic process; and protein homotetramerization. Predicted to localize to several cellular components, including the 6-phosphofructokinase complex; apical plasma membrane; and sperm principal piece. Human ortholog(s) of this gene implicated in glycogen storage disease VII. Orthologous to human PFKM (phosphofructokinase, muscle); PARTICIPATES IN Fanconi syndrome pathway; glycogen storage disease type VII pathway; glycolysis pathway; INTERACTS WITH (RS)-amphetamine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 6-phosphofructokinase type A; 6-phosphofructokinase, muscle type; ATP-dependent 6-phosphofructokinase, muscle type; ATP-PFK; PFK-A; Pfk-M; phosphofructo-1-kinase isozyme A; phosphofructokinase 1; phosphofructokinase-A; phosphofructokinase-M; phosphohexokinase
Orthologs:
Homo sapiens (human) : PFKM (phosphofructokinase, muscle)  HGNC  Alliance
Mus musculus (house mouse) : Pfkm (phosphofructokinase, muscle)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pfkm (phosphofructokinase, muscle)
Pan paniscus (bonobo/pygmy chimpanzee) : PFKM (phosphofructokinase, muscle)
Canis lupus familiaris (dog) : PFKM (phosphofructokinase, muscle)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pfkm (phosphofructokinase, muscle)
Sus scrofa (pig) : PFKM (phosphofructokinase, muscle)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.07139,702,066 - 139,722,132 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.07138,837,772 - 138,857,276 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47136,826,122 - 136,846,040 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17136,898,639 - 136,922,477 (+)NCBI
Celera7125,730,934 - 125,751,002 (+)NCBICelera
Cytogenetic Map7q36NCBI
RH 3.4 Map71088.6RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Pfkm
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 68419
Created: 2001-07-11
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.