Gene: Dlg4 (discs large MAGUK scaffold protein 4) Rattus norvegicus
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Symbol: Dlg4
Name: discs large MAGUK scaffold protein 4
Description: Exhibits several functions, including PDZ domain binding activity, enzyme binding activity, and signaling receptor binding activity; involved in several processes, including generation of neurons, protein localization to membrane, and regulation of signal transduction; localizes to several cellular components, including the anchored component of postsynaptic density membrane, cell-cell junction, and neuron projection; colocalizes with the voltage-gated potassium channel complex; biomarker of Parkinson's disease and temporal lobe epilepsy; orthologous to human DLG4 (discs large MAGUK scaffold protein 4); PARTICIPATES IN glutamate signaling pathway; Huntington's disease pathway; INTERACTS WITH (RS)-amphetamine; (S)-nicotine; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: discs large homolog 4; discs, large homolog 4; discs, large homolog 4 (Drosophila); disks large homolog 4; Dlgh4; postsynaptic density protein 95; PSD-95; PSD95; SAP-90; Sap90; synapse-associated protein 90; synapse-associated protein SAP90
Orthologs:
Homo sapiens (human) : DLG4 (discs large MAGUK scaffold protein 4)  HGNC  Alliance
Mus musculus (house mouse) : Dlg4 (discs large MAGUK scaffold protein 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dlg4 (discs large MAGUK scaffold protein 4)
Pan paniscus (bonobo/pygmy chimpanzee) : DLG4 (discs large MAGUK scaffold protein 4)
Canis lupus familiaris (dog) : DLG4 (discs large MAGUK scaffold protein 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dlg4 (discs large MAGUK scaffold protein 4)
Sus scrofa (pig) : DLG4 (discs large MAGUK scaffold protein 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01056,625,845 - 56,655,543 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01056,369,703 - 56,400,662 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41056,864,459 - 56,890,626 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11056,878,081 - 56,904,246 (+)NCBI
Celera1053,894,685 - 53,920,691 (+)NCBICelera
Cytogenetic Map10q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Dlg4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 68424
Created: 2001-07-11
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.