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Gene: Pde10a (phosphodiesterase 10A) Rattus norvegicus
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Symbol: Pde10a
Name: phosphodiesterase 10A
Description: Exhibits cyclic-nucleotide phosphodiesterase activity. Involved in negative regulation of cAMP-mediated signaling and negative regulation of cGMP-mediated signaling. Localizes to the membrane and perikaryon. Orthologous to human PDE10A (phosphodiesterase 10A); PARTICIPATES IN adenine phoshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; adenylosuccinate lyase deficiency pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A; Pde10a3; testis-specific phosphodiesterase PDE10A2
Orthologs:
Homo sapiens (human) : PDE10A (phosphodiesterase 10A)  HGNC  Alliance
Mus musculus (house mouse) : Pde10a (phosphodiesterase 10A)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pde10a (phosphodiesterase 10A)
Pan paniscus (bonobo/pygmy chimpanzee) : PDE10A (phosphodiesterase 10A)
Canis lupus familiaris (dog) : PDE10A (phosphodiesterase 10A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pde10a (phosphodiesterase 10A)
Sus scrofa (pig) : PDE10A (phosphodiesterase 10A)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0152,360,296 - 52,544,448 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0153,617,430 - 53,800,479 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4146,392,900 - 46,589,076 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1146,395,844 - 46,592,020 (-)NCBI
Celera147,539,418 - 47,723,290 (-)NCBICelera
Cytogenetic Map1q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Pde10a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 68434
Created: 2001-07-11
Species: Rattus norvegicus
Last Modified: 2019-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.