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Gene: POR (cytochrome p450 oxidoreductase) Homo sapiens
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Symbol: POR
Name: cytochrome p450 oxidoreductase
Description: Exhibits NADPH-hemoprotein reductase activity. Involved in cellular organofluorine metabolic process; oxidation-reduction process; and positive regulation of monooxygenase activity. Localizes to the intracellular membrane-bounded organelle. Implicated in Antley-Bixler syndrome and congenital adrenal hyperplasia.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CPR; CYPOR; DKFZp686G04235; FLJ26468; NADPH--cytochrome P450 reductase; NADPH--hemoprotein reductase; NADPH-dependent cytochrome P450 reductase; P450 (cytochrome) oxidoreductase; P450R
Orthologs:
Mus musculus (house mouse) : Por (P450 (cytochrome) oxidoreductase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Por (cytochrome p450 oxidoreductase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Por (P450 (cytochrome) oxidoreductase)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100990437 (NADPH--cytochrome P450 reductase)
Canis lupus familiaris (dog) : POR (cytochrome p450 oxidoreductase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101965545 (NADPH--cytochrome P450 reductase)
Sus scrofa (pig) : POR (P450 (cytochrome) oxidoreductase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38775,915,155 - 75,986,855 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37775,544,420 - 75,616,173 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36775,382,356 - 75,454,109 (+)NCBINCBI36hg18NCBI36
Build 34775,227,957 - 75,260,823NCBI
Celera770,412,991 - 70,484,717 (+)NCBI
Cytogenetic Map7q11.23NCBI
HuRef770,631,215 - 70,702,985 (+)NCBIHuRef
CHM1_1775,474,511 - 75,546,243 (+)NCBICHM1_1
CRA_TCAGchr7v2774,877,484 - 74,949,237 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on POR
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 68468
Created: 2001-07-11
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.