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Gene: CUBN (cubilin) Homo sapiens
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Symbol: CUBN
Name: cubilin
Description: Exhibits protein homodimerization activity. Predicted to be involved in several processes, including cobalamin metabolic process; cobalamin transport; and high-density lipoprotein particle clearance. Localizes to the apical plasma membrane; endocytic vesicle; and extracellular exosome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 460 kDa receptor; cubilin (intrinsic factor-cobalamin receptor); cubilin precursor variant 1; cubilin precursor variant 2; cubilin precursor variant 3; FLJ90055; FLJ90747; gp280; IFCR; intestinal intrinsic factor receptor; intrinsic factor B12-receptor; intrinsic factor-cobalamin receptor; intrinsic factor-vitamin B12 receptor; MGA1
Orthologs:
Mus musculus (house mouse) : Cubn (cubilin (intrinsic factor-cobalamin receptor))  MGI  Alliance
Rattus norvegicus (Norway rat) : Cubn (cubilin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cubn (cubilin)
Pan paniscus (bonobo/pygmy chimpanzee) : CUBN (cubilin)
Canis lupus familiaris (dog) : CUBN (cubilin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cubn (cubilin)
Sus scrofa (pig) : CUBN (cubilin)
more info ...
Related Pseudogenes: CUBNP1   CUBNP3  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381016,823,966 - 17,130,492 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371016,865,965 - 17,171,816 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361016,905,971 - 17,211,822 (-)NCBINCBI36hg18NCBI36
Build 341016,906,543 - 17,211,796NCBI
Celera1016,799,178 - 17,105,066 (-)NCBI
Cytogenetic Map10p13NCBI
HuRef1016,779,758 - 17,084,998 (-)NCBIHuRef
CHM1_11016,866,152 - 17,171,970 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CUBN
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 68502
Created: 2001-07-11
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.