Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: SIGMAR1 (sigma non-opioid intracellular receptor 1) Homo sapiens
Analyze
Symbol: SIGMAR1
Name: sigma non-opioid intracellular receptor 1
Description: Exhibits identical protein binding activity. Involved in protein homotrimerization and regulation of neuron apoptotic process. Localizes to several cellular components, including the endoplasmic reticulum; nuclear envelope; and postsynaptic density. Implicated in amyotrophic lateral sclerosis type 16 and distal spinal muscular atrophy 2.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: aging-associated gene 8 protein; ALS16; DSMA2; FLJ25585; hSigmaR1; MGC3851; opioid receptor, sigma 1; OPRS1; SIG-1R; sigma 1-type opioid receptor; sigma1 receptor; sigma1-receptor; sigma1R; SR-BP; SR-BP1; SR31747 binding protein 1; SR31747-binding protein; SRBP; type I sigma receptor
Orthologs:
Mus musculus (house mouse) : Sigmar1 (sigma non-opioid intracellular receptor 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Sigmar1 (sigma non-opioid intracellular receptor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sigmar1 (sigma non-opioid intracellular receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SIGMAR1 (sigma non-opioid intracellular receptor 1)
Canis lupus familiaris (dog) : SIGMAR1 (sigma non-opioid intracellular receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sigmar1 (sigma non-opioid intracellular receptor 1)
Sus scrofa (pig) : SIGMAR1 (sigma non-opioid intracellular receptor 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38934,634,722 - 34,637,826 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37934,634,719 - 34,637,805 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36934,624,719 - 34,627,768 (-)NCBINCBI36hg18NCBI36
Build 34934,624,719 - 34,627,768NCBI
Celera934,566,222 - 34,569,271 (-)NCBI
Cytogenetic Map9p13.3NCBI
HuRef934,589,001 - 34,592,050 (-)NCBIHuRef
CHM1_1934,634,494 - 34,637,593 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on SIGMAR1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 68519
Created: 2001-07-11
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.