Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Sigmar1 (sigma non-opioid intracellular receptor 1) Mus musculus
Symbol: Sigmar1
Name: sigma non-opioid intracellular receptor 1
Description: Exhibits signaling receptor activity. Involved in cell death in response to hydrogen peroxide. Localizes to postsynaptic density. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 16 and distal spinal muscular atrophy 2. Is expressed in several structures, including central nervous system; genitourinary system; hemolymphoid system gland; intraembryonic coelom; and liver. Orthologous to human SIGMAR1 (sigma non-opioid intracellular receptor 1).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AL024364; mSigmaR1; opioid receptor, sigma 1; Oprs1; Sig1R; sigma 1 receptor variant SR-1D; sigma 1-type opioid receptor; sigma1-receptor; sigma1R
Homo sapiens (human) : SIGMAR1 (sigma non-opioid intracellular receptor 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Sigmar1 (sigma non-opioid intracellular receptor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sigmar1 (sigma non-opioid intracellular receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SIGMAR1 (sigma non-opioid intracellular receptor 1)
Canis lupus familiaris (dog) : SIGMAR1 (sigma non-opioid intracellular receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sigmar1 (sigma non-opioid intracellular receptor 1)
Sus scrofa (pig) : SIGMAR1 (sigma non-opioid intracellular receptor 1)
Heterocephalus glaber (naked mole-rat) : Sigmar1 (sigma non-opioid intracellular receptor 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl441,738,493 - 41,756,157 (-)EnsemblGRCm38mm10GRCm38
GRCm38441,738,493 - 41,741,359 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37441,685,369 - 41,688,186 (-)NCBIGRCm37mm9NCBIm37
MGSCv36441,927,007 - 41,929,824 (-)NCBImm8
Celera441,399,281 - 41,402,095 (-)NCBICelera
Cytogenetic Map4A5NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Sigmar1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 68520
Created: 2001-07-11
Species: Mus musculus
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.