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Gene: Grid2 (glutamate receptor, ionotropic, delta 2) Mus musculus
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Symbol: Grid2
Name: glutamate receptor, ionotropic, delta 2
Description: Exhibits PDZ domain binding activity and scaffold protein binding activity. Involved in several processes, including cerebellar granule cell differentiation; chemical synaptic transmission; and regulation of nervous system development. Localizes to several cellular components, including glutamatergic synapse; integral component of plasma membrane; and parallel fiber to Purkinje cell synapse. Used to study autosomal recessive spinocerebellar ataxia 18. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 18. Is expressed in several structures, including brain; eye; genitourinary system; intestine; and spinal cord. Orthologous to human GRID2 (glutamate ionotropic receptor delta type subunit 2); PARTICIPATES IN long term depression; INTERACTS WITH (S)-nicotine; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; arsenous acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: B230104L07Rik; cpr; creeper; GluD2; gluR delta-2 subunit; GluRdelta2; glutamate receptor delta-2 subunit; glutamate receptor ionotropic, delta-2; ho; hotfoot; Lc; Lc; lurcher; minisatellite 10ac detected by probe MMS10; MMS10-AC; Ms10ac; nmf408; tpr
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl663,255,876 - 64,704,323 (+)EnsemblGRCm38mm10GRCm38
GRCm38663,256,006 - 64,704,321 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37663,206,851 - 64,616,273 (+)NCBIGRCm37mm9NCBIm37
MGSCv36663,186,435 - 64,595,857 (+)NCBImm8
Celera665,396,130 - 66,793,674 (+)NCBICelera
Cytogenetic Map6C1NCBI
cM Map629.77NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
 
More on Grid2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 68528
Created: 2001-07-11
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.