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Gene: Ctbp2 (C-terminal binding protein 2) Mus musculus
Symbol: Ctbp2
Name: C-terminal binding protein 2
Description: Exhibits chromatin binding activity; retinoic acid receptor binding activity; and transcription coregulator activity. Involved in several processes, including cellular response to leukemia inhibitory factor; positive regulation of retinoic acid receptor signaling pathway; and regulation of transcription, DNA-templated. Localizes to several cellular components, including photoreceptor ribbon synapse; presynaptic active zone cytoplasmic component; and presynaptic cytosol. Is expressed in several structures, including alimentary system; eye; integumental system; limb; and nervous system. Orthologous to human CTBP2 (C-terminal binding protein 2); PARTICIPATES IN chronic myeloid leukemia pathway; Notch signaling pathway; Wnt signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4-hydroxyphenyl retinamide; 4-methylthio-2-oxobutanoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA407280; C-terminal-binding protein 2; D7Ertd45e; gene trap ROSA b-geo 6; Gtrgeo6; Ribeye
Homo sapiens (human) : CTBP2 (C-terminal binding protein 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ctbp2 (C-terminal binding protein 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ctbp2 (C-terminal binding protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CTBP2 (C-terminal binding protein 2)
Canis lupus familiaris (dog) : CTBP2 (C-terminal binding protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ctbp2 (C-terminal binding protein 2)
Sus scrofa (pig) : CTBP2 (C-terminal binding protein 2)
Chlorocebus sabaeus (African green monkey) : CTBP2 (C-terminal binding protein 2)
Heterocephalus glaber (naked mole-rat) : Ctbp2 (C-terminal binding protein 2)
more info ...
Related Pseudogenes: Gm18403  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl7132,987,563 - 133,124,354 (-)EnsemblGRCm38mm10GRCm38
GRCm387132,986,998 - 133,124,009 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv377140,178,694 - 140,315,166 (-)NCBIGRCm37mm9NCBIm37
MGSCv367132,825,913 - 132,961,691 (-)NCBImm8
Celera7132,792,998 - 132,952,787 (-)NCBICelera
Cytogenetic Map7F3NCBI
cM Map776.32NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ctbp2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 68536
Created: 2001-07-11
Species: Mus musculus
Last Modified: 2020-06-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.