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Gene: Cacnb4 (calcium channel, voltage-dependent, beta 4 subunit) Mus musculus
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Symbol: Cacnb4
Name: calcium channel, voltage-dependent, beta 4 subunit
Description: Exhibits voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels. Involved in several processes, including adult walking behavior; cellular response to leukemia inhibitory factor; and hematopoietic or lymphoid organ development. Localizes to the glutamatergic synapse and voltage-gated calcium channel complex. Human ortholog(s) of this gene implicated in dilated cardiomyopathy; episodic ataxia; episodic ataxia type 5; and idiopathic generalized epilepsy 9. Is expressed in cerebellum; heart; and telencephalon. Orthologous to human CACNB4 (calcium voltage-gated channel auxiliary subunit beta 4); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; arrhythmogenic right ventricular cardiomyopathy pathway; INTERACTS WITH 1,1-dichloroethene; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 3110038O15Rik; CAB4; calcium channel voltage-dependent subunit beta 4; Cchb4; lethargic; lh; MGC31529; voltage-dependent L-type calcium channel subunit beta-4
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38252,428,320 - 52,676,609 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37252,283,840 - 52,532,101 (-)NCBIGRCm37mm9NCBIm37
MGSCv36252,250,329 - 52,498,591 (-)NCBImm8
Celera254,158,343 - 54,407,181 (-)NCBICelera
Cytogenetic Map2 C1.1NCBI
cM Map229.98NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
 
More on Cacnb4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 68559
Created: 2001-07-11
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.