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Gene: KCND3 (potassium voltage-gated channel subfamily D member 3) Homo sapiens
Symbol: KCND3
Name: potassium voltage-gated channel subfamily D member 3
Description: Exhibits ion channel binding activity. Contributes to A-type (transient outward) potassium channel activity and voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization. Involved in potassium ion export across plasma membrane; regulation of heart rate by cardiac conduction; and ventricular cardiac muscle cell membrane repolarization. Localizes to the voltage-gated potassium channel complex. Implicated in Brugada syndrome 9 and spinocerebellar ataxia type 19/22.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BRGDA9; KCND3L; KCND3S; KSHIVB; KV4.3; MGC142035; MGC142037; potassium channel, voltage gated Shal related subfamily D, member 3; potassium ionic channel Kv4.3; potassium voltage-gated channel long; potassium voltage-gated channel, Shal-related subfamily, member 3; SCA19; SCA22; sha1-related potassium channel Kv4.3; spinocerebellar ataxia 19; spinocerebellar ataxia 22; voltage-gated K+ channel; voltage-gated potassium channel Kv4.3; voltage-gated potassium channel subunit Kv4.3
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1111,770,662 - 111,989,155 (-)EnsemblGRCh38hg38GRCh38
GRCh381111,770,662 - 111,989,577 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371112,318,444 - 112,532,147 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361112,119,977 - 112,333,300 (-)NCBINCBI36hg18NCBI36
Build 341112,030,495 - 112,243,819NCBI
Celera1110,565,074 - 110,778,378 (-)NCBI
Cytogenetic Map1p13.2NCBI
HuRef1110,189,856 - 110,403,378 (-)NCBIHuRef
CHM1_11112,433,439 - 112,646,758 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on KCND3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 68576
Created: 2001-07-11
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.