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Gene: CLDN1 (claudin 1) Homo sapiens
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Symbol: CLDN1
Name: claudin 1
Description: Exhibits virus receptor activity. Involved in several processes, including bicellular tight junction assembly; establishment of skin barrier; and protein complex oligomerization. Localizes to several cellular components, including the basolateral plasma membrane; bicellular tight junction; and integral component of plasma membrane. Implicated in Crohn's disease and atopic dermatitis. Biomarker of atopic dermatitis and irritable bowel syndrome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: claudin-1; CLD1; ILVASC; SEMP1; senescence-associated epithelial membrane protein 1
Orthologs:
Mus musculus (house mouse) : Cldn1 (claudin 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cldn1 (claudin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cldn1 (claudin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CLDN1 (claudin 1)
Canis lupus familiaris (dog) : CLDN1 (claudin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cldn1 (claudin 1)
Sus scrofa (pig) : CLDN1 (claudin 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383190,305,707 - 190,322,446 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh373190,023,490 - 190,040,235 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363191,506,187 - 191,522,909 (-)NCBINCBI36hg18NCBI36
Build 343191,506,195 - 191,522,917NCBI
Celera3188,453,968 - 188,470,713 (-)NCBI
Cytogenetic Map3q28NCBI
HuRef3187,423,222 - 187,439,968 (-)NCBIHuRef
CHM1_13189,986,455 - 190,003,201 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on CLDN1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 68626
Created: 2001-07-11
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.