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Gene: PDE10A (phosphodiesterase 10A) Homo sapiens
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Symbol: PDE10A
Name: phosphodiesterase 10A
Description: Exhibits cAMP binding activity and cGMP-stimulated cyclic-nucleotide phosphodiesterase activity. Predicted to be involved in negative regulation of cGMP-mediated signaling. Predicted to localize to the cytosol.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 3',5' cAMP/cGMP phosphodiesterase; ADSD2; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A; dJ416F21.1 (phosphodiesterase 10A); FLJ11894; FLJ25677; HSPDE10A; IOLOD; LINC00473; PDE10A19; phosphodiesterase 10A1 (PDE10A1); phosphodiesterase 10A7 (PDE10A7)
Orthologs:
Mus musculus (house mouse) : Pde10a (phosphodiesterase 10A)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pde10a (phosphodiesterase 10A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pde10a (phosphodiesterase 10A)
Pan paniscus (bonobo/pygmy chimpanzee) : PDE10A (phosphodiesterase 10A)
Canis lupus familiaris (dog) : PDE10A (phosphodiesterase 10A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pde10a (phosphodiesterase 10A)
Sus scrofa (pig) : PDE10A (phosphodiesterase 10A)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386165,327,287 - 165,988,115 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh376165,740,776 - 166,075,588 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366165,664,519 - 165,995,574 (-)NCBINCBI36hg18NCBI36
Build 346165,714,945 - 166,045,996NCBI
Celera6166,478,886 - 166,814,271 (-)NCBI
Cytogenetic Map6q27NCBI
HuRef6163,202,267 - 163,537,621 (-)NCBIHuRef
CHM1_16166,003,719 - 166,338,432 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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References - uncurated

Genomics

Comparative Map Data
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Expression


Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
 
More on PDE10A
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 68649
Created: 2001-07-11
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.