Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Bhlhe40 (basic helix-loop-helix family, member e40) Mus musculus
Symbol: Bhlhe40
Name: basic helix-loop-helix family, member e40
Description: Exhibits several functions, including DNA-binding transcription factor binding activity; DNA-binding transcription repressor activity, RNA polymerase II-specific; and RNA polymerase II regulatory region sequence-specific DNA binding activity. Involved in circadian regulation of gene expression; entrainment of circadian clock by photoperiod; and negative regulation of transcription, DNA-templated. Localizes to the nucleus. Is expressed in several structures, including brain; early conceptus; embryo mesenchyme; genitourinary system; and lower leg. Orthologous to human BHLHE40 (basic helix-loop-helix family member e40).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: basic helix-loop-helix domain containing, class B2; Bhlhb2; C130042M06Rik; class B basic helix-loop-helix protein 2; class E basic helix-loop-helix protein 40; Clast5; CR8; cytokine response gene 8; Dec1; differentially expressed in chondrocytes protein 1; E47 interaction protein 1; eip1 (E47 interaction protein 1); Sharp2; stimulated by retinoic acid gene 13 protein; Stra13; Stra14
Homo sapiens (human) : BHLHE40 (basic helix-loop-helix family member e40)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Bhlhe40 (basic helix-loop-helix family, member e40)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bhlhe40 (basic helix-loop-helix family member e40)
Pan paniscus (bonobo/pygmy chimpanzee) : BHLHE40 (basic helix-loop-helix family member e40)
Canis lupus familiaris (dog) : BHLHE40 (basic helix-loop-helix family member e40)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bhlhe40 (basic helix-loop-helix family member e40)
Sus scrofa (pig) : BHLHE40 (basic helix-loop-helix family member e40)
Chlorocebus sabaeus (African green monkey) : BHLHE40 (basic helix-loop-helix family member e40)
Heterocephalus glaber (naked mole-rat) : Bhlhe40 (basic helix-loop-helix family member e40)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl6108,660,629 - 108,666,925 (+)Ensembl
GRCm386108,660,629 - 108,666,925 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv376108,610,623 - 108,616,919 (+)NCBIGRCm37mm9NCBIm37
MGSCv366108,626,406 - 108,632,702 (+)NCBImm8
Celera6110,461,756 - 110,468,060 (+)NCBICelera
Cytogenetic Map6 E2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Bhlhe40
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 68660
Created: 2001-07-11
Species: Mus musculus
Last Modified: 2020-01-14
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.