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Gene: Tbp (TATA box binding protein) Mus musculus
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Symbol: Tbp
Name: TATA box binding protein
Description: Exhibits RNA polymerase II proximal promoter sequence-specific DNA binding activity and RNA polymerase II repressing transcription factor binding activity. Involved in transcription by RNA polymerase II and transcription by RNA polymerase III. Localizes to the cytoplasm; female pronucleus; and male pronucleus. Used to study spinocerebellar ataxia type 17. Human ortholog(s) of this gene implicated in hereditary ataxia; late onset Parkinson's disease; schizophrenia; spinocerebellar ataxia type 17; and type 1 diabetes mellitus. Is expressed in several structures, including brain; early conceptus; genitourinary system; limb; and retina. Orthologous to human TBP (TATA-box binding protein); PARTICIPATES IN cisplatin drug pathway; RNA polymerase I transcription pathway; RNA polymerase II transcription initiation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; Aroclor 1254; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Gtf2d; GTF2D1; SCA17; TATA sequence-binding protein; TATA-binding factor; TATA-binding protein; TATA-box factor; TATA-box-binding protein; TFIID; TFIID core protein; transcription initiation factor TFIID TBP subunit
Orthologs:
Homo sapiens (human) : TBP (TATA-box binding protein)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tbp (TATA box binding protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tbp (TATA-box binding protein)
Pan paniscus (bonobo/pygmy chimpanzee) : TBP (TATA-box binding protein)
Canis lupus familiaris (dog) : TBP (TATA-box binding protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tbp (TATA-box binding protein)
Sus scrofa (pig) : TBP (TATA-box binding protein)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381715,499,888 - 15,517,427 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371715,636,852 - 15,654,391 (+)NCBIGRCm37mm9NCBIm37
MGSCv361715,208,038 - 15,221,746 (+)NCBImm8
Celera1716,285,165 - 16,302,716 (+)NCBICelera
Cytogenetic Map17 A2NCBI
cM Map178.95NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Tbp
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 68981
Created: 2001-11-06
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.