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Gene: PTGES (prostaglandin E synthase) Homo sapiens
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Symbol: PTGES
Name: prostaglandin E synthase
Description: Exhibits glutathione binding activity and prostaglandin-E synthase activity. Involved in prostaglandin biosynthetic process. Localizes to the integral component of membrane. Biomarker of carcinoma (multiple); endometriosis (multiple); in situ carcinoma (multiple); and penile neoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: glutathione S-transferase 1-like 1; MGC10317; MGST-IV; MGST1-L1; MGST1-like 1; MGST1L1; microsomal glutathione S-transferase 1-like 1; microsomal prostaglandin E synthase 1; microsomal prostaglandin E synthase-1; MPGES; mPGES-1; p53-induced apoptosis protein 12; p53-induced gene 12 protein; PGES; PIG12; PP102; PP1294; TP53I12; tumor protein p53 inducible protein 12
Orthologs:
Mus musculus (house mouse) : Ptges (prostaglandin E synthase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ptges (prostaglandin E synthase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ptges (prostaglandin E synthase)
Pan paniscus (bonobo/pygmy chimpanzee) : PTGES (prostaglandin E synthase)
Canis lupus familiaris (dog) : PTGES (prostaglandin E synthase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ptges (prostaglandin E synthase)
Sus scrofa (pig) : PTGES (prostaglandin E synthase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389129,738,349 - 129,753,042 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh379132,500,615 - 132,515,344 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369131,540,433 - 131,555,165 (-)NCBINCBI36hg18NCBI36
Build 349129,580,165 - 129,594,898NCBI
Celera9103,151,433 - 103,166,162 (-)NCBI
Cytogenetic Map9q34.11NCBI
HuRef9102,099,772 - 102,114,492 (-)NCBIHuRef
CHM1_19132,649,284 - 132,663,955 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on PTGES
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 69032
Created: 2001-11-06
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.