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Gene: PTGES (prostaglandin E synthase) Homo sapiens
Symbol: PTGES
Name: prostaglandin E synthase
Description: Exhibits glutathione binding activity and prostaglandin-E synthase activity. Involved in prostaglandin biosynthetic process. Localizes to the integral component of membrane. Biomarker of carcinoma (multiple); endometriosis (multiple); in situ carcinoma (multiple); and penile neoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: glutathione S-transferase 1-like 1; MGC10317; MGST-IV; MGST1-L1; MGST1-like 1; MGST1L1; microsomal glutathione S-transferase 1-like 1; microsomal prostaglandin E synthase 1; microsomal prostaglandin E synthase-1; MPGES; mPGES-1; p53-induced apoptosis protein 12; p53-induced gene 12 protein; PGES; PIG12; PP102; PP1294; TP53I12; tumor protein p53 inducible protein 12
Mus musculus (house mouse) : Ptges (prostaglandin E synthase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ptges (prostaglandin E synthase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ptges (prostaglandin E synthase)
Pan paniscus (bonobo/pygmy chimpanzee) : PTGES (prostaglandin E synthase)
Canis lupus familiaris (dog) : PTGES (prostaglandin E synthase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ptges (prostaglandin E synthase)
Sus scrofa (pig) : PTGES (prostaglandin E synthase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh389129,738,349 - 129,753,042 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh379132,500,615 - 132,515,344 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369131,540,433 - 131,555,165 (-)NCBINCBI36hg18NCBI36
Build 349129,580,165 - 129,594,898NCBI
Celera9103,151,433 - 103,166,162 (-)NCBI
Cytogenetic Map9q34.11NCBI
HuRef9102,099,772 - 102,114,492 (-)NCBIHuRef
CHM1_19132,649,284 - 132,663,955 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on PTGES
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 69032
Created: 2001-11-06
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.