Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: TGFB1 (transforming growth factor beta 1) Homo sapiens
Analyze
Symbol: TGFB1
Name: transforming growth factor beta 1
Description: Exhibits several functions, including antigen binding activity; identical protein binding activity; and transforming growth factor beta receptor binding activity. Involved in several processes, including animal organ development; cell surface receptor signaling pathway; and positive regulation of cellular metabolic process. Localizes to several cellular components, including the cell surface; extracellular space; and nucleus. Colocalizes with the microvillus. Implicated in several diseases, including Behcet's disease; aphthous stomatitis; artery disease (multiple); bone disease (multiple); and lung disease (multiple). Biomarker of several diseases, including artery disease (multiple); autoimmune hypersensitivity disease (multiple); carcinoma (multiple); hematologic cancer (multiple); and lung disease (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CED; DPD1; IBDIMDE; LAP; latency-associated peptide; prepro-transforming growth factor beta-1; TGF-beta 1 protein; TGF-beta-1; TGF-beta1; TGFB; TGFbeta; transforming growth factor beta-1; transforming growth factor beta-1 proprotein; transforming growth factor beta1
Orthologs:
Mus musculus (house mouse) : Tgfb1 (transforming growth factor, beta 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tgfb1 (transforming growth factor, beta 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tgfb1 (transforming growth factor beta 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TGFB1 (transforming growth factor beta 1)
Canis lupus familiaris (dog) : B9D2 (B9 domain containing 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tgfb1 (transforming growth factor beta 1)
Sus scrofa (pig) : TGFB1 (transforming growth factor beta 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381941,330,323 - 41,353,922 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371941,836,812 - 41,859,831 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361946,528,491 - 46,551,656 (-)NCBINCBI36hg18NCBI36
Build 341946,528,658 - 46,551,158NCBI
Celera1938,636,964 - 38,659,992 (-)NCBI
Cytogenetic Map19q13.2NCBI
HuRef1938,268,902 - 38,291,920 (-)NCBIHuRef
CHM1_11941,836,128 - 41,859,502 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations