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Gene: Tgfb1 (transforming growth factor, beta 1) Mus musculus
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Symbol: Tgfb1
Name: transforming growth factor, beta 1
Description: Exhibits protein serine/threonine kinase activator activity and transforming growth factor beta receptor binding activity. Involved in several processes, including animal organ development; positive regulation of cell differentiation; and regulation of cellular protein localization. Localizes to the extracellular matrix and extracellular space. Predicted to colocalize with the microvillus. Used to study Sjogren's syndrome. Human ortholog(s) of this gene implicated in several diseases, including Behcet's disease; aphthous stomatitis; artery disease (multiple); bone disease (multiple); and lung disease (multiple). Is expressed in several structures, including alimentary system; embryo mesenchyme; genitourinary system; heart; and skin. Orthologous to human TGFB1 (transforming growth factor beta 1).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: regulatory protein; TGF-beta 1; TGF-beta-1; TGF-beta1; Tgfb; Tgfb-1; TGFbeta1; transforming growth factor beta-1; transforming growth factor beta-1 proprotein; transforming growth factor-beta 1
Orthologs:
Homo sapiens (human) : TGFB1 (transforming growth factor beta 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tgfb1 (transforming growth factor, beta 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tgfb1 (transforming growth factor beta 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TGFB1 (transforming growth factor beta 1)
Canis lupus familiaris (dog) : B9D2 (B9 domain containing 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tgfb1 (transforming growth factor beta 1)
Sus scrofa (pig) : TGFB1 (transforming growth factor beta 1)
Chlorocebus sabaeus (green monkey) : TGFB1 (transforming growth factor beta 1)
Heterocephalus glaber (naked mole-rat) : Tgfb1 (transforming growth factor beta 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl725,687,002 - 25,705,077 (+)Ensembl
GRCm38725,687,002 - 25,705,077 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37726,472,021 - 26,490,015 (+)NCBIGRCm37mm9NCBIm37
MGSCv36725,395,762 - 25,413,756 (+)NCBImm8
Celera720,295,914 - 20,313,908 (+)NCBICelera
Cytogenetic Map7 A3NCBI
cM Map713.98NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model