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Gene: Kcnj11 (potassium inwardly rectifying channel, subfamily J, member 11) Mus musculus
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Symbol: Kcnj11
Name: potassium inwardly rectifying channel, subfamily J, member 11
Description: Exhibits ATP binding activity; ATP-activated inward rectifier potassium channel activity; and ankyrin binding activity. Involved in potassium ion import across plasma membrane. Localizes to the T-tubule and inward rectifying potassium channel. Used to study permanent neonatal diabetes mellitus. Human ortholog(s) of this gene implicated in familial hyperinsulinemic hypoglycemia 2 and glucose metabolism disease (multiple). Is expressed in several structures, including brain; cardiovascular system; gut; skeletal muscle tissue; and testis. Orthologous to human KCNJ11 (potassium inwardly rectifying channel subfamily J member 11); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; altered insulin secretion pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrophenol; 2-deoxy-D-glucose.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI842722; ATP-sensitive inward rectifier potassium channel 11; AW491124; inward rectifier K(+) channel Kir6.2; Kir6.2; mBIR; potassium channel, inwardly rectifying subfamily J member 11; potassium unwardly rectifying channel, subfamily J, member 11
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl746,093,953 - 46,100,764 (-)Ensembl
GRCm38746,097,123 - 46,100,952 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37753,352,532 - 53,355,607 (-)NCBIGRCm37mm9NCBIm37
MGSCv36745,965,204 - 45,968,279 (-)NCBImm8
Celera741,570,444 - 41,574,072 (-)NCBICelera
Cytogenetic Map7 B3NCBI
cM Map729.66NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
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Expression


Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
 
More on Kcnj11
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 69099
Created: 2001-11-08
Species: Mus musculus
Last Modified: 2019-12-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.