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Gene: NR1I2 (nuclear receptor subfamily 1 group I member 2) Homo sapiens
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Symbol: NR1I2
Name: nuclear receptor subfamily 1 group I member 2
Description: Exhibits DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II regulatory region sequence-specific DNA binding activity; and drug binding activity. Involved in several processes, including exogenous drug catabolic process; regulation of transcription, DNA-templated; and xenobiotic transport. Localizes to the intermediate filament cytoskeleton and nuclear body.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BXR; nuclear receptor subfamily 1, group 1, member 2; nuclear receptor subfamily 1, group I, member 2; ONR1; orphan nuclear receptor PAR1; orphan nuclear receptor PXR; PAR; PAR1; PAR2; PARq; pregnane X nuclear receptor variant 2; pregnane X receptor; PRR; PXR; SAR; steroid and xenobiotic receptor; SXR
Orthologs:
Mus musculus (house mouse) : Nr1i2 (nuclear receptor subfamily 1, group I, member 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nr1i2 (nuclear receptor subfamily 1, group I, member 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nr1i2 (nuclear receptor subfamily 1 group I member 2)
Pan paniscus (bonobo/pygmy chimpanzee) : NR1I2 (nuclear receptor subfamily 1 group I member 2)
Canis lupus familiaris (dog) : NR1I2 (nuclear receptor subfamily 1 group I member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nr1i2 (nuclear receptor subfamily 1 group I member 2)
Sus scrofa (pig) : NR1I2 (nuclear receptor subfamily 1 group I member 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383119,780,484 - 119,818,485 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh373119,499,331 - 119,552,295 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363120,982,021 - 121,020,022 (+)NCBINCBI36hg18NCBI36
Build 343120,982,020 - 121,020,021NCBI
Celera3117,908,432 - 117,946,438 (+)NCBI
Cytogenetic Map3q13.33NCBI
HuRef3116,874,950 - 116,913,074 (+)NCBIHuRef
CHM1_13119,462,845 - 119,500,855 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on NR1I2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 69105
Created: 2001-11-08
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.