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Gene: Nr1i2 (nuclear receptor subfamily 1, group I, member 2) Mus musculus
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Symbol: Nr1i2
Name: nuclear receptor subfamily 1, group I, member 2
Description: Predicted to have several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II regulatory region sequence-specific DNA binding activity; and nuclear receptor transcription coactivator activity. Involved in positive regulation of gene expression. Predicted to localize to the RNA polymerase II transcription factor complex; intermediate filament cytoskeleton; and nuclear body. Is expressed in several structures, including branchial arch; ear; genitourinary system; heart; and nervous system. Orthologous to human NR1I2 (nuclear receptor subfamily 1 group I member 2); INTERACTS WITH (+)-schisandrin B; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1,1-dichloroethene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: mPXR; nuclear receptor subfamily 1 group I member 2; orphan nuclear receptor PXR; Pregnane X receptor; PXR; PXR.1; PXR.2; PXR1; SXR
Orthologs:
Homo sapiens (human) : NR1I2 (nuclear receptor subfamily 1 group I member 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Nr1i2 (nuclear receptor subfamily 1, group I, member 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nr1i2 (nuclear receptor subfamily 1 group I member 2)
Pan paniscus (bonobo/pygmy chimpanzee) : NR1I2 (nuclear receptor subfamily 1 group I member 2)
Canis lupus familiaris (dog) : NR1I2 (nuclear receptor subfamily 1 group I member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nr1i2 (nuclear receptor subfamily 1 group I member 2)
Sus scrofa (pig) : NR1I2 (nuclear receptor subfamily 1 group I member 2)
Chlorocebus sabaeus (green monkey) : NR1I2 (nuclear receptor subfamily 1 group I member 2)
Heterocephalus glaber (naked mole-rat) : Nr1i2 (nuclear receptor subfamily 1 group I member 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1638,248,323 - 38,294,824 (-)Ensembl
GRCm381638,248,349 - 38,294,849 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371638,248,435 - 38,294,910 (-)NCBIGRCm37mm9NCBIm37
MGSCv361638,167,590 - 38,214,062 (-)NCBImm8
Celera1638,657,356 - 38,703,953 (-)NCBICelera
Cytogenetic Map16 B3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Nr1i2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 69106
Created: 2001-11-08
Species: Mus musculus
Last Modified: 2020-01-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.