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Gene: PTH (parathyroid hormone) Homo sapiens
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Symbol: PTH
Name: parathyroid hormone
CRRD ID: 69107
Description: Exhibits protein N-terminus binding activity and signaling receptor binding activity. Involved in several processes, including activation of phospholipase C activity; positive regulation of cellular biosynthetic process; and positive regulation of glucose import. Predicted to localize to extracellular space. Implicated in several diseases, including chronic kidney disease; diabetes mellitus (multiple); familial isolated hypoparathyroidism; hyperphosphatemia; and secondary hyperparathyroidism. Biomarker of several diseases, including artery disease (multiple); atrophic gastritis; calcium oxalate nephrolithiasis; chronic kidney disease (multiple); and hyperparathyroidism (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FIH1; parathormone; parathyrin; parathyroid hormone 1; prepro-PTH; preproparathyroid hormone; PTH1
Orthologs:
Mus musculus (house mouse) : Pth (parathyroid hormone)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pth (parathyroid hormone)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pth (parathyroid hormone)
Pan paniscus (bonobo/pygmy chimpanzee) : PTH (parathyroid hormone)
Canis lupus familiaris (dog) : PTH (parathyroid hormone)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pth (parathyroid hormone)
Sus scrofa (pig) : PTH (parathyroid hormone)
Chlorocebus sabaeus (African green monkey) : PTH (parathyroid hormone)
Heterocephalus glaber (naked mole-rat) : Pth (parathyroid hormone)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1113,492,054 - 13,496,181 (-)EnsemblGRCh38hg38GRCh38
GRCh381113,492,054 - 13,496,181 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371113,513,601 - 13,517,567 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361113,470,177 - 13,474,143 (-)NCBINCBI36hg18NCBI36
Build 341113,470,177 - 13,474,143NCBI
Celera1113,639,772 - 13,643,738 (-)NCBI
Cytogenetic Map11p15.3NCBI
HuRef1113,193,715 - 13,197,681 (-)NCBIHuRef
CHM1_11113,512,562 - 13,516,692 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on PTH
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 69107
Created: 2001-11-08
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.