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Gene: CEBPA (CCAAT enhancer binding protein alpha) Homo sapiens
Symbol: CEBPA
Name: CCAAT enhancer binding protein alpha
Description: Exhibits several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase I regulatory region DNA binding activity; and kinase binding activity. Involved in several processes, including interleukin-6-mediated signaling pathway; positive regulation of transcription, DNA-templated; and transcription by RNA polymerase I. Localizes to the RNA polymerase II transcription factor complex; nucleolus; and nucleoplasm. Implicated in acute myeloid leukemia. Biomarker of Alzheimer's disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: c/EBP alpha; C/EBP-alpha; CCAAT/enhancer binding protein (C/EBP), alpha; CCAAT/enhancer binding protein alpha; ccaat/enhancer binding protein, alpha; CCAAT/enhancer-binding protein alpha; CEBP
Mus musculus (house mouse) : Cebpa (CCAAT/enhancer binding protein (C/EBP), alpha)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cebpa (CCAAT/enhancer binding protein alpha)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cebpa (CCAAT enhancer binding protein alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : CEBPA (CCAAT enhancer binding protein alpha)
Canis lupus familiaris (dog) : CEBPA (CCAAT enhancer binding protein alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cebpa (CCAAT enhancer binding protein alpha)
Sus scrofa (pig) : CEBPA (CCAAT enhancer binding protein alpha)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1933,299,934 - 33,302,534 (-)Ensembl
GRCh381933,299,934 - 33,302,564 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371933,790,840 - 33,793,430 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361938,482,776 - 38,485,160 (-)NCBINCBI36hg18NCBI36
Build 341938,482,775 - 38,485,160NCBI
Celera1930,484,405 - 30,486,995 (-)NCBI
Cytogenetic Map19q13.11NCBI
HuRef1930,291,676 - 30,294,205 (-)NCBIHuRef
CHM1_11933,791,795 - 33,794,425 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on CEBPA
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 69121
Created: 2001-11-08
Species: Homo sapiens
Last Modified: 2020-01-07
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.