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Gene: BTG2 (BTG anti-proliferation factor 2) Homo sapiens
Symbol: BTG2
Name: BTG anti-proliferation factor 2
Description: Predicted to have DNA-binding transcription repressor activity, RNA polymerase II-specific. Involved in several processes, including negative regulation of cell population proliferation; neuron projection development; and regulation of gene expression. Localizes to extracellular exosome. Biomarker of brain ischemia; breast cancer; prostate carcinoma in situ; and renal cell carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: APRO1; B-cell translocation gene 2; b-cell translocation gene 2, anti-proliferative; BTG family member 2; BTG family, member 2; MGC126063; MGC126064; nerve growth factor-inducible anti-proliferative; NGF-inducible anti-proliferative protein PC3; PC3; pheochromacytoma cell-3; TIS21
Mus musculus (house mouse) : Btg2 (BTG anti-proliferation factor 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Btg2 (BTG anti-proliferation factor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Btg2 (BTG anti-proliferation factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : BTG2 (BTG anti-proliferation factor 2)
Canis lupus familiaris (dog) : BTG2 (BTG anti-proliferation factor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Btg2 (BTG anti-proliferation factor 2)
Sus scrofa (pig) : BTG2 (BTG anti-proliferation factor 2)
Chlorocebus sabaeus (African green monkey) : BTG2 (BTG anti-proliferation factor 2)
Heterocephalus glaber (naked mole-rat) : Btg2 (BTG anti-proliferation factor 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1203,305,491 - 203,309,602 (+)EnsemblGRCh38hg38GRCh38
GRCh381203,305,519 - 203,309,602 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371203,274,664 - 203,278,730 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361201,541,287 - 201,545,353 (+)NCBINCBI36hg18NCBI36
Build 341200,006,320 - 200,010,384NCBI
Celera1176,403,938 - 176,408,003 (+)NCBI
Cytogenetic Map1q32.1NCBI
HuRef1174,439,723 - 174,443,788 (+)NCBIHuRef
CHM1_11204,697,045 - 204,701,100 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on BTG2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 69157
Created: 2001-11-08
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.