Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: CYP7A1 (cytochrome P450 family 7 subfamily A member 1) Homo sapiens
Analyze
Symbol: CYP7A1
Name: cytochrome P450 family 7 subfamily A member 1
Description: Exhibits cholesterol 7-alpha-monooxygenase activity. Involved in bile acid biosynthetic process; cellular response to glucose stimulus; and regulation of bile acid biosynthetic process. Predicted to localize to the intracellular membrane-bounded organelle.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 24-hydroxycholesterol 7-alpha-hydroxylase; cholesterol 7-alpha-hydroxylase; cholesterol 7-alpha-monooxygenase; CP7A; CYP7; CYPVII; cytochrome P450 7A1; cytochrome P450, family 7, subfamily A, polypeptide 1; cytochrome P450, subfamily VIIA polypeptide 1; MGC126826; MGC138389
Orthologs:
Mus musculus (house mouse) : Cyp7a1 (cytochrome P450, family 7, subfamily a, polypeptide 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cyp7a1 (cytochrome P450 family 7 subfamily A member 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : LOC102008593 (cholesterol 7-alpha-monooxygenase)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100991402 (cholesterol 7-alpha-monooxygenase)
Canis lupus familiaris (dog) : CYP7A1 (cytochrome P450 family 7 subfamily A member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101970910 (cholesterol 7-alpha-monooxygenase)
Sus scrofa (pig) : CYP7A1 (cytochrome P450, family 7, subfamily A, polypeptide 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl858,490,178 - 58,500,163 (-)Ensembl
GRCh38858,490,178 - 58,500,163 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37859,402,737 - 59,412,720 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36859,565,292 - 59,575,275 (-)NCBINCBI36hg18NCBI36
Build 34859,565,291 - 59,575,275NCBI
Celera855,395,751 - 55,405,734 (-)NCBI
Cytogenetic Map8q12.1NCBI
HuRef854,889,962 - 54,899,885 (-)NCBIHuRef
CHM1_1859,454,626 - 59,464,609 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CYP7A1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 69210
Created: 2001-11-13
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.