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Gene: Gpx3 (glutathione peroxidase 3) Rattus norvegicus
Symbol: Gpx3
Name: glutathione peroxidase 3
CRRD ID: 69224
Description: Exhibits glutathione peroxidase activity and selenium binding activity. Involved in several processes, including hydrogen peroxide catabolic process; response to corticosterone; and response to molecule of fungal origin. Localizes to extracellular space. Biomarker of endometrial adenocarcinoma; lung disease; and obesity. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human GPX3 (glutathione peroxidase 3); PARTICIPATES IN arachidonic acid metabolic pathway; glutathione metabolic pathway; INTERACTS WITH 17beta-estradiol; 2,2,2-tetramine; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: GPx-3; GPx-P; Gpxp; GSHPx-3; GSHPx-P; plasma glutathione peroxidase; plasma glutathione peroxidase precursor
Homo sapiens (human) : GPX3 (glutathione peroxidase 3)  HGNC  Alliance
Mus musculus (house mouse) : Gpx3 (glutathione peroxidase 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gpx3 (glutathione peroxidase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : GPX3 (glutathione peroxidase 3)
Canis lupus familiaris (dog) : GPX3 (glutathione peroxidase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gpx3 (glutathione peroxidase 3)
Sus scrofa (pig) : GPX3 (glutathione peroxidase 3)
Chlorocebus sabaeus (African green monkey) : GPX3 (glutathione peroxidase 3)
Heterocephalus glaber (naked mole-rat) : Gpx3 (glutathione peroxidase 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01040,247,436 - 40,255,423 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1040,247,436 - 40,255,422 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01040,019,704 - 40,027,691 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41040,311,094 - 40,319,382 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11040,324,744 - 40,333,004 (+)NCBI
Celera1038,366,821 - 38,374,734 (+)NCBICelera
Cytogenetic Map10q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Gpx3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 69224
Created: 2001-11-14
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.