Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Hnrnpa1 (heterogeneous nuclear ribonucleoprotein A1) Rattus norvegicus
Symbol: Hnrnpa1
Name: heterogeneous nuclear ribonucleoprotein A1
Description: Exhibits nucleic acid binding activity and transcription factor binding activity. Involved in several processes, including cellular response to epidermal growth factor stimulus; cellular response to thapsigargin; and cellular response to tunicamycin. Localizes to cytosol and nucleoplasmic periphery of the nuclear pore complex. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 20; inclusion body myopathy with early-onset Paget disease of bone with or without frontotemporal dementia 3; and tropical spastic paraparesis. Orthologous to several human genes including HNRNPA1L2 (heterogeneous nuclear ribonucleoprotein A1 like 2); PARTICIPATES IN spliceosome pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,4-dibromophenyl 2,4,5-tribromophenyl ether.
Type: protein-coding
Also known as: HDP; helix-destabilizing protein; hnRNP A1; hnRNP core protein A1; Hnrpa1; single-strand RNA-binding protein
Homo sapiens (human) : HNRNPA1 (heterogeneous nuclear ribonucleoprotein A1)  HGNC  Alliance
Mus musculus (house mouse) : Hnrnpa1 (heterogeneous nuclear ribonucleoprotein A1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hnrnpa1 (heterogeneous nuclear ribonucleoprotein A1)
Pan paniscus (bonobo/pygmy chimpanzee) : HNRNPA1 (heterogeneous nuclear ribonucleoprotein A1)
Canis lupus familiaris (dog) : HNRNPA1 (heterogeneous nuclear ribonucleoprotein A1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hnrnpa1 (heterogeneous nuclear ribonucleoprotein A1)
Sus scrofa (pig) : HNRNPA1 (heterogeneous nuclear ribonucleoprotein A1)
Chlorocebus sabaeus (African green monkey) : HNRNPA1 (heterogeneous nuclear ribonucleoprotein A1)
Heterocephalus glaber (naked mole-rat) : Hnrnpa1 (heterogeneous nuclear ribonucleoprotein A1)
more info ...
Related Pseudogenes: Hnrnpa1-ps1  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.07144,865,302 - 144,871,592 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7144,865,608 - 144,871,585 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07142,647,071 - 142,652,967 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47142,150,229 - 142,154,520 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17142,230,417 - 142,234,709 (+)NCBI
Celera7130,801,278 - 130,805,569 (+)NCBICelera
Cytogenetic Map7q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Hnrnpa1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 69234
Created: 2001-11-14
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.