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Gene: Impa1 (inositol monophosphatase 1) Rattus norvegicus
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Symbol: Impa1
Name: inositol monophosphatase 1
Description: Exhibits inositol monophosphate 1-phosphatase activity and metal ion binding activity. Involved in inositol phosphate dephosphorylation; phosphatidylinositol biosynthetic process; and response to lithium ion. Localizes to axon and neuronal cell body. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human IMPA1 (inositol monophosphatase 1); PARTICIPATES IN inositol metabolic pathway; inositol phosphate metabolic pathway; phosphatidylinositol 3-kinase signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: D-galactose 1-phosphate phosphatase; IMP 1; Impa1-L; IMPase 1; Inositol (myo)-1(or 4)-monophosphatase 1; inositol-1(or 4)-monophosphatase 1; lithium-sensitive myo-inositol monophosphatase A1
Orthologs:
Homo sapiens (human) : IMPA1 (inositol monophosphatase 1)  HGNC  Alliance
Mus musculus (house mouse) : Impa1 (inositol (myo)-1(or 4)-monophosphatase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Impa1 (inositol monophosphatase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : IMPA1 (inositol monophosphatase 1)
Canis lupus familiaris (dog) : IMPA1 (inositol monophosphatase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Impa1 (inositol monophosphatase 1)
Sus scrofa (pig) : IMPA1 (inositol monophosphatase 1)
Chlorocebus sabaeus (African green monkey) : IMPA1 (inositol monophosphatase 1)
Heterocephalus glaber (naked mole-rat) : Impa1 (inositol monophosphatase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0293,675,203 - 93,696,355 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl293,675,203 - 93,696,232 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02113,430,723 - 113,453,209 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4293,415,958 - 93,438,247 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1293,360,919 - 93,383,209 (+)NCBI
Celera287,065,842 - 87,086,646 (+)NCBICelera
Cytogenetic Map2q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Impa1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 69254
Created: 2001-11-14
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.