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Gene: Aplp1 (amyloid beta precursor like protein 1) Rattus norvegicus
Symbol: Aplp1
Name: amyloid beta precursor like protein 1
CRRD ID: 69257
Description: Predicted to have adrenergic receptor binding activity and identical protein binding activity. Predicted to be involved in several processes, including cellular response to norepinephrine stimulus; mRNA polyadenylation; and negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to localize to Golgi apparatus; perinuclear region of cytoplasm; and plasma membrane. Orthologous to human APLP1 (amyloid beta precursor like protein 1); INTERACTS WITH (+)-pilocarpine; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
Also known as: amyloid beta (A4) precursor-like protein 1; amyloid beta (A4) precursor-like protein 1 (mapped); amyloid-like protein 1; Aplp1_mapped; Aplp1_retired; LOC502317; RGD1561211; similar to Amyloid beta (A4) precursor-like protein 1
Homo sapiens (human) : APLP1 (amyloid beta precursor like protein 1)  HGNC  Alliance
Mus musculus (house mouse) : Aplp1 (amyloid beta (A4) precursor-like protein 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Aplp1 (amyloid beta precursor like protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : APLP1 (amyloid beta precursor like protein 1)
Canis lupus familiaris (dog) : APLP1 (amyloid beta precursor like protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aplp1 (amyloid beta precursor like protein 1)
Sus scrofa (pig) : APLP1 (amyloid beta precursor like protein 1)
Chlorocebus sabaeus (African green monkey) : APLP1 (amyloid beta precursor like protein 1)
Heterocephalus glaber (naked mole-rat) : Aplp1 (amyloid beta precursor like protein 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0188,897,525 - 88,908,750 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl188,897,532 - 88,908,750 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0190,053,390 - 90,063,110 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4185,390,217 - 85,401,952 (-)NCBIRGSC3.4rn4RGSC3.4
Celera180,069,348 - 80,079,276 (-)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Aplp1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 69257
Created: 2001-11-14
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.