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Gene: Slc5a7 (solute carrier family 5 member 7) Rattus norvegicus
Symbol: Slc5a7
Name: solute carrier family 5 member 7
CRRD ID: 69270
Description: Exhibits choline transmembrane transporter activity. Involved in acetylcholine biosynthetic process. Localizes to several cellular components, including cytoplasmic vesicle; perikaryon; and plasma membrane raft. Biomarker of asthma. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 20 and distal hereditary motor neuronopathy type 7A. Orthologous to human SLC5A7 (solute carrier family 5 member 7); PARTICIPATES IN acetylcholine signaling pathway via muscarinic acetylcholine receptor; acetylcholine signaling pathway via nicotinic acetylcholine receptor; INTERACTS WITH (S)-nicotine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil.
Type: protein-coding
Also known as: CHT; Cht1; hemicholinium-3-sensitive choline transporter; high affinity choline transporter 1; solute carrier family 5 (choline transporter) member 7; solute carrier family 5 (choline transporter), member 7; solute carrier family 5 (sodium/choline cotransporter), member 7; solute carrier family 5, member 7
Homo sapiens (human) : SLC5A7 (solute carrier family 5 member 7)  HGNC  Alliance
Mus musculus (house mouse) : Slc5a7 (solute carrier family 5 (choline transporter), member 7)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc5a7 (solute carrier family 5 member 7)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC5A7 (solute carrier family 5 member 7)
Canis lupus familiaris (dog) : SLC5A7 (solute carrier family 5 member 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc5a7 (solute carrier family 5 member 7)
Sus scrofa (pig) : SLC5A7 (solute carrier family 5 member 7)
Chlorocebus sabaeus (African green monkey) : SLC5A7 (solute carrier family 5 member 7)
Heterocephalus glaber (naked mole-rat) : Slc5a7 (solute carrier family 5 member 7)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.095,294,377 - 5,330,822 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl95,294,381 - 5,330,815 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.094,342,128 - 4,379,724 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.49133,838 - 165,943 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.19133,837 - 165,939 (+)NCBI
Celera93,418,007 - 3,448,801 (-)NCBICelera
Cytogenetic Map9q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Slc5a7
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 69270
Created: 2001-11-14
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.