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Gene: Socs2 (suppressor of cytokine signaling 2) Rattus norvegicus
Symbol: Socs2
Name: suppressor of cytokine signaling 2
Description: Predicted to have 1-phosphatidylinositol-3-kinase regulator activity; growth hormone receptor binding activity; and insulin-like growth factor receptor binding activity. Involved in aging and response to peptide hormone. Predicted to localize to phosphatidylinositol 3-kinase complex. Human ortholog(s) of this gene implicated in endometrial cancer and ovarian carcinoma. Orthologous to human SOCS2 (suppressor of cytokine signaling 2); PARTICIPATES IN interleukin-2 signaling pathway; Jak-Stat signaling pathway; insulin signaling pathway; INTERACTS WITH 1,3-dinitrobenzene; 1-naphthyl isothiocyanate; 3H-1,2-dithiole-3-thione.
Type: protein-coding
Also known as: Cish2; cytokine inducible SH2-containing protein 2; cytokine-inducible SH2 protein 2; Socs-2
Homo sapiens (human) : SOCS2 (suppressor of cytokine signaling 2)  HGNC  Alliance
Mus musculus (house mouse) : Socs2 (suppressor of cytokine signaling 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Socs2 (suppressor of cytokine signaling 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SOCS2 (suppressor of cytokine signaling 2)
Canis lupus familiaris (dog) : SOCS2 (suppressor of cytokine signaling 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Socs2 (suppressor of cytokine signaling 2)
Sus scrofa (pig) : SOCS2 (suppressor of cytokine signaling 2)
Chlorocebus sabaeus (African green monkey) : SOCS2 (suppressor of cytokine signaling 2)
Heterocephalus glaber (naked mole-rat) : Socs2 (suppressor of cytokine signaling 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0736,495,496 - 36,500,878 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl736,495,480 - 36,499,784 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0736,558,014 - 36,560,623 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4732,605,714 - 32,608,323 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1732,625,999 - 32,628,594 (-)NCBI
Celera727,114,252 - 27,116,861 (-)NCBICelera
Cytogenetic Map7q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Socs2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 69273
Created: 2001-11-14
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.