Gene: Casp2 (caspase 2) Rattus norvegicus
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Symbol: Casp2
Name: caspase 2
Description: Predicted to have cysteine-type endopeptidase activity involved in apoptotic process, identical protein binding activity, and protein domain specific binding activity; involved in several processes, including aging, animal organ development, and apoptotic process; localizes to the membrane and mitochondrion; biomarker of status epilepticus; orthologous to human CASP2 (caspase 2); INTERACTS WITH (R)-noradrenaline; (RS)-amphetamine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CASP-2; caspase-2; ICH-1 protease; protease ICH-1
Orthologs:
Homo sapiens (human) : CASP2 (caspase 2)  HGNC  Alliance
Mus musculus (house mouse) : Casp2 (caspase 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Casp2 (caspase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CASP2 (caspase 2)
Canis lupus familiaris (dog) : CASP2 (caspase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Casp2 (caspase 2)
Sus scrofa (pig) : CASP2 (caspase 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0471,652,358 - 71,670,228 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04136,454,723 - 136,474,625 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4470,029,728 - 70,047,164 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1470,305,857 - 70,323,294 (+)NCBI
Celera466,080,364 - 66,098,003 (+)NCBICelera
Cytogenetic Map4q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Casp2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 69274
Created: 2001-11-14
Species: Rattus norvegicus
Last Modified: 2019-04-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.