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Gene: Cdh2 (cadherin 2) Rattus norvegicus
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Symbol: Cdh2
Name: cadherin 2
Description: Exhibits beta-catenin binding activity; nitric-oxide synthase binding activity; and protein kinase binding activity. Involved in several processes, including calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; regulation of glutamatergic synaptic transmission; and regulation of nervous system development. Localizes to several cellular components, including T-tubule; fascia adherens; and integral component of synaptic membrane. Predicted to colocalize with cortical actin cytoskeleton. Human ortholog(s) of this gene implicated in arrhythmogenic right ventricular cardiomyopathy. Orthologous to human CDH2 (cadherin 2); PARTICIPATES IN cadherin mediated signaling pathway; fibroblast growth factor signaling pathway; N-cadherin signaling pathway; INTERACTS WITH (+)-pilocarpine; 1,1-bis(2-aminoethyl)-2-hydroxy-3-oxotriazane; 1,3-dinitrobenzene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: cadherin 2 type 1 N-cadherin (neuronal); cadherin 2, type 1, N-cadherin (neuronal); cadherin-2; N-cadherin; neural cadherin
Orthologs:
Homo sapiens (human) : CDH2 (cadherin 2)  HGNC  Alliance
Mus musculus (house mouse) : Cdh2 (cadherin 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdh2 (cadherin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CDH2 (cadherin 2)
Canis lupus familiaris (dog) : CDH2 (cadherin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdh2 (cadherin 2)
Sus scrofa (pig) : CDH2 (cadherin 2)
Chlorocebus sabaeus (African green monkey) : CDH2 (cadherin 2)
Heterocephalus glaber (naked mole-rat) : Cdh2 (cadherin 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0188,146,971 - 8,366,037 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl188,146,971 - 8,360,684 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0187,997,533 - 8,218,018 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4188,048,920 - 8,267,974 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1188,048,919 - 8,268,462 (-)NCBI
Celera187,938,006 - 8,155,134 (-)NCBICelera
Cytogenetic Map18p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cdh2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 69280
Created: 2001-11-14
Species: Rattus norvegicus
Last Modified: 2020-05-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.