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Gene: St14 (ST14 transmembrane serine protease matriptase) Rattus norvegicus
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Symbol: St14
Name: ST14 transmembrane serine protease matriptase
CRRD ID: 69288
Description: Exhibits serine-type peptidase activity. Involved in proteolysis. Localizes to basolateral plasma membrane; extracellular space; and extrinsic component of plasma membrane. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 11. Orthologous to human ST14 (ST14 transmembrane serine protease matriptase); INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: matriptase; membrane-type serine protease; MT-SP1; suppression of tumorigenicity 14; suppression of tumorigenicity 14 (colon carcinoma matriptase epithin); suppression of tumorigenicity 14 (colon carcinoma); suppression of tumorigenicity 14 (colon carcinoma, matriptase, epithin)
Orthologs:
Homo sapiens (human) : ST14 (ST14 transmembrane serine protease matriptase)  HGNC  Alliance
Mus musculus (house mouse) : St14 (suppression of tumorigenicity 14 (colon carcinoma))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : St14 (ST14 transmembrane serine protease matriptase)
Pan paniscus (bonobo/pygmy chimpanzee) : ST14 (ST14 transmembrane serine protease matriptase)
Canis lupus familiaris (dog) : ST14 (ST14 transmembrane serine protease matriptase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : St14 (ST14 transmembrane serine protease matriptase)
Sus scrofa (pig) : ST14 (ST14 transmembrane serine protease matriptase)
Chlorocebus sabaeus (African green monkey) : ST14 (ST14 transmembrane serine protease matriptase)
Heterocephalus glaber (naked mole-rat) : St14 (ST14 transmembrane serine protease matriptase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0832,240,113 - 32,280,813 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl832,240,133 - 32,280,869 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0832,266,158 - 32,305,925 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4830,916,769 - 30,932,214 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1830,925,535 - 30,940,977 (-)NCBI
Celera831,002,596 - 31,042,887 (-)NCBICelera
Cytogenetic Map8q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on St14
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 69288
Created: 2001-11-14
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.