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Gene: Litaf (lipopolysaccharide-induced TNF factor) Rattus norvegicus
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Symbol: Litaf
Name: lipopolysaccharide-induced TNF factor
Description: Predicted to have RNA polymerase II proximal promoter sequence-specific DNA binding activity; WW domain binding activity; and zinc ion binding activity. Involved in aging. Predicted to localize to several cellular components, including the cytoplasmic side of endosome membrane; cytoplasmic side of lysosomal membrane; and cytoplasmic side of plasma membrane. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 1C. Orthologous to human LITAF (lipopolysaccharide induced TNF factor); INTERACTS WITH (+)-schisandrin B; 1,3,5-trinitro-1,3,5-triazinane; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: EET-1; estrogen-enhanced transcript protein 1; estrogen-responsive uterine transcript; lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog; LPS-induced TN factor; LPS-induced TNF-alpha factor; LPS-induced TNF-alpha factor homolog; Pig7
Orthologs:
Homo sapiens (human) : LITAF (lipopolysaccharide induced TNF factor)  HGNC  Alliance
Mus musculus (house mouse) : Litaf (LPS-induced TN factor)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Litaf (lipopolysaccharide induced TNF factor)
Pan paniscus (bonobo/pygmy chimpanzee) : LITAF (lipopolysaccharide induced TNF factor)
Canis lupus familiaris (dog) : LITAF (lipopolysaccharide induced TNF factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Litaf (lipopolysaccharide induced TNF factor)
Sus scrofa (pig) : LITAF (lipopolysaccharide induced TNF factor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0104,753,546 - 4,763,272 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl104,719,713 - 4,763,510 (+)Ensembl
Rnor_5.0103,580,243 - 3,589,969 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4104,614,177 - 4,623,903 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1104,587,486 - 4,623,903 (+)NCBI
Celera103,704,946 - 3,714,672 (+)NCBICelera
Cytogenetic Map10q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Litaf
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 69294
Created: 2001-11-14
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.