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Gene: Fxyd1 (FXYD domain-containing ion transport regulator 1) Rattus norvegicus
Symbol: Fxyd1
Name: FXYD domain-containing ion transport regulator 1
Description: Exhibits ATPase binding activity and myosin binding activity. Involved in several processes, including positive regulation of transport; regulation of cardiac muscle cell contraction; and regulation of cytosolic calcium ion concentration. Localizes to several cellular components, including the T-tubule; caveola; and intercalated disc. Biomarker of congestive heart failure. Orthologous to human FXYD1 (FXYD domain containing ion transport regulator 1); INTERACTS WITH (+)-schisandrin B; (RS)-amphetamine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: phospholemman; Plm; sodium/potassium-transporting ATPase subunit FXYD1
Homo sapiens (human) : FXYD1 (FXYD domain containing ion transport regulator 1)  HGNC  Alliance
Mus musculus (house mouse) : Fxyd1 (FXYD domain-containing ion transport regulator 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fxyd1 (FXYD domain containing ion transport regulator 1)
Pan paniscus (bonobo/pygmy chimpanzee) : FXYD1 (FXYD domain containing ion transport regulator 1)
Canis lupus familiaris (dog) : FXYD1 (FXYD domain containing ion transport regulator 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fxyd1 (FXYD domain containing ion transport regulator 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0189,484,197 - 89,488,279 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0190,639,290 - 90,643,385 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4186,095,551 - 86,098,079 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1186,173,662 - 86,176,167 (-)NCBI
Celera180,656,116 - 80,660,202 (-)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Fxyd1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 69306
Created: 2001-11-14
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.