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Gene: Hadh (hydroxyacyl-CoA dehydrogenase) Rattus norvegicus
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Symbol: Hadh
Name: hydroxyacyl-CoA dehydrogenase
Description: Exhibits 3-hydroxyacyl-CoA dehydrogenase activity. Involved in several processes, including fatty acid beta-oxidation; negative regulation of insulin secretion; and response to activity. Predicted to localize to the mitochondrion and nucleoplasm. Biomarker of myocardial infarction and obesity. Human ortholog(s) of this gene implicated in familial hyperinsulinemic hypoglycemia 4. Orthologous to human HADH (hydroxyacyl-CoA dehydrogenase); PARTICIPATES IN fatty acid beta degradation pathway; 2-aminoadipic 2-oxoadipic aciduria pathway; 3-hydroxyacyl-CoA dehydrogenase deficiency pathway; INTERACTS WITH (+)-schisandrin B; (R)-adrenaline; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Hadhsc; HCDH; hydroxyacyl-Coenzyme A dehydrogenase; hydroxyacyl-coenzyme A dehydrogenase, mitochondrial; hydroxylacyl-Coenzyme A dehydrogenase; hydroxylacyl-Coenzyme A dehydrogenase short chain; hydroxylacyl-Coenzyme A dehydrogenase, short chain; L-3-hydroxyacyl-Coenzyme A dehydrogenase, short chain; medium and short chain L-3-hydroxyacyl-coenzyme A dehydrogenase; medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase; short chain 3-hydroxyacyl-CoA dehydrogenase; short-chain 3-hydroxyacyl-CoA dehydrogenase
Orthologs:
Homo sapiens (human) : HADH (hydroxyacyl-CoA dehydrogenase)  HGNC  Alliance
Mus musculus (house mouse) : Hadh (hydroxyacyl-Coenzyme A dehydrogenase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hadh (hydroxyacyl-CoA dehydrogenase)
Pan paniscus (bonobo/pygmy chimpanzee) : HADH (hydroxyacyl-CoA dehydrogenase)
Canis lupus familiaris (dog) : HADH (hydroxyacyl-CoA dehydrogenase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hadh (hydroxyacyl-CoA dehydrogenase)
Sus scrofa (pig) : HADH (hydroxyacyl-CoA dehydrogenase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02236,353,445 - 236,395,067 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02254,902,140 - 254,944,001 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42228,698,545 - 228,751,691 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12228,685,284 - 228,738,431 (-)NCBI
Celera2212,044,254 - 212,086,368 (-)NCBICelera
Cytogenetic Map2q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Hadh
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 69321
Created: 2001-11-14
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.