Gene: Erbb3 (erb-b2 receptor tyrosine kinase 3) Rattus norvegicus
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Symbol: Erbb3
Name: erb-b2 receptor tyrosine kinase 3
Description: Exhibits neuregulin binding activity and neuregulin receptor activity; involved in several processes, including animal organ development, axonogenesis, and cellular response to insulin stimulus; localizes to the nucleus and postsynaptic membrane; biomarker of chronic obstructive pulmonary disease and median neuropathy; orthologous to human ERBB3 (erb-b2 receptor tyrosine kinase 3); PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; angiotensin II signaling pathway via AT2 receptor; calcium/calcium-mediated signaling pathway; INTERACTS WITH (RS)-amphetamine; 6-propyl-2-thiouracil; aldehydo-D-glucose.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: avian erythroblastosis oncogene B 3; c-erbB-3; c-erbB3; nuc-ErbB3; proto-oncogene-like protein c-ErbB-3; receptor tyrosine-protein kinase erbB-3; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
Orthologs:
Homo sapiens (human) : ERBB3 (erb-b2 receptor tyrosine kinase 3)  HGNC  Alliance
Mus musculus (house mouse) : Erbb3 (erb-b2 receptor tyrosine kinase 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Erbb3 (erb-b2 receptor tyrosine kinase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : ERBB3 (erb-b2 receptor tyrosine kinase 3)
Canis lupus familiaris (dog) : ERBB3 (erb-b2 receptor tyrosine kinase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Erbb3 (erb-b2 receptor tyrosine kinase 3)
Sus scrofa (pig) : ERBB3 (erb-b2 receptor tyrosine kinase 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.072,989,202 - 3,010,610 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.072,962,964 - 2,984,938 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.471,858,057 - 1,877,353 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.171,858,056 - 1,877,353 (-)NCBI
Celera7866,587 - 885,873 (-)NCBICelera
Cytogenetic Map7q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Erbb3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 69323
Created: 2001-11-14
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.