Gene: Mapt (microtubule-associated protein tau) Rattus norvegicus
Analyze
Symbol: Mapt
Name: microtubule-associated protein tau
Description: Exhibits several functions, including Hsp90 protein binding activity, chaperone binding activity, and enzyme binding activity; involved in several processes, including female pregnancy, intrinsic apoptotic signaling pathway in response to oxidative stress, and nervous system development; localizes to several cellular components, including the cytoplasmic side of plasma membrane, cytosol, and neuron projection; predicted to colocalize with the membrane; used to study several diseases, including cerebrovascular disease (multiple), cognitive disorder, epilepsy, obesity, and tauopathy (multiple); biomarker of middle cerebral artery infarction; orthologous to human MAPT (microtubule associated protein tau); PARTICIPATES IN Reelin signaling pathway; Alzheimer's disease pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine; 2,4-dibromophenyl 2,4,5-tribromophenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MGC156663; Mtapt; neurofibrillary tangle protein; paired helical filament-tau; PHF-tau; pTau; RNPTAU; Tau; Tau microtubule-associated protein
Orthologs:
Homo sapiens (human) : MAPT (microtubule associated protein tau)  HGNC  Alliance
Mus musculus (house mouse) : Mapt (microtubule-associated protein tau)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mapt (microtubule associated protein tau)
Pan paniscus (bonobo/pygmy chimpanzee) : MAPT (microtubule associated protein tau)
Canis lupus familiaris (dog) : MAPT (microtubule associated protein tau)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mapt (microtubule associated protein tau)
Sus scrofa (pig) : MAPT (microtubule associated protein tau)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01092,289,002 - 92,386,517 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01092,050,754 - 92,147,840 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41093,411,098 - 93,508,762 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11093,425,375 - 93,523,128 (+)NCBI
Celera1087,832,730 - 87,930,191 (+)NCBICelera
Cytogenetic Map10q32.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Mapt
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 69329
Created: 2001-11-14
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.