Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Scn9a (sodium voltage-gated channel alpha subunit 9) Rattus norvegicus
Analyze
Symbol: Scn9a
Name: sodium voltage-gated channel alpha subunit 9
Description: Exhibits sodium ion binding activity and voltage-gated sodium channel activity. Involved in neuronal action potential. Localizes to axon and voltage-gated sodium channel complex. Human ortholog(s) of this gene implicated in Dravet syndrome; erythromelalgia; generalized epilepsy with febrile seizures plus 7; and paroxysmal extreme pain disorder. Orthologous to human SCN9A (sodium voltage-gated channel alpha subunit 9); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Nav1.7; peripheral sodium channel 1; PN1; Scn2a; sodium channel protein type 9 subunit alpha; sodium channel protein type IX subunit alpha; sodium channel type IX alpha polypeptide; sodium channel voltage-gated type IX alpha polypeptide; sodium channel, voltage-gated, type 9, alpha polypeptide; sodium channel, voltage-gated, type IX, alpha; sodium channel, voltage-gated, type IX, alpha polypeptide; sodium channel, voltage-gated, type IX, alpha subunit; voltage-gated sodium channel subunit alpha Nav1.7
Orthologs:
Homo sapiens (human) : SCN9A (sodium voltage-gated channel alpha subunit 9)  HGNC  Alliance
Mus musculus (house mouse) : Scn9a (sodium channel, voltage-gated, type IX, alpha)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Scn9a (sodium voltage-gated channel alpha subunit 9)
Pan paniscus (bonobo/pygmy chimpanzee) : SCN9A (sodium voltage-gated channel alpha subunit 9)
Canis lupus familiaris (dog) : SCN9A (sodium voltage-gated channel alpha subunit 9)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Scn9a (sodium voltage-gated channel alpha subunit 9)
Sus scrofa (pig) : SCN9A (sodium voltage-gated channel alpha subunit 9)
Chlorocebus sabaeus (African green monkey) : SCN9A (sodium voltage-gated channel alpha subunit 9)
Heterocephalus glaber (naked mole-rat) : Scn9a (sodium voltage-gated channel alpha subunit 9)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0352,583,953 - 52,664,209 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl352,583,951 - 52,664,209 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0359,207,264 - 59,286,961 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4348,438,725 - 48,518,893NCBIRGSC3.4rn4RGSC3.4
Celera350,729,098 - 50,808,151 (-)NCBICelera
Cytogenetic Map3q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Scn9a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 69368
Created: 2001-11-14
Species: Rattus norvegicus
Last Modified: 2020-07-14
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.