Gene: Sik1 (salt-inducible kinase 1) Rattus norvegicus
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Symbol: Sik1
Name: salt-inducible kinase 1
Description: Exhibits protein kinase binding activity and protein serine/threonine kinase activity; involved in negative regulation of transcription by RNA polymerase II, protein phosphorylation, and regulation of sodium ion transport; localizes to the cytosol and nucleus; orthologous to several human genes including SIK1B (salt inducible kinase 1B (putative)); INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 2,6-dinitrotoluene; 2-ethoxyethanol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: protein kinase KID2; salt-inducible protein kinase; salt-inducible protein kinase 1; serine/threonine-protein kinase SIK1; serine/threonine-protein kinase SNF1-like kinase 1; serine/threonine-protein kinase SNF1LK; Sik; SIK-1; SNF1-like kinase; Snf1lk
Orthologs:
Homo sapiens (human) : SIK1 (salt inducible kinase 1)  HGNC  Alliance
Mus musculus (house mouse) : Sik1 (salt inducible kinase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sik1 (salt inducible kinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SIK1 (salt inducible kinase 1)
Canis lupus familiaris (dog) : SIK1 (salt inducible kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sik1 (salt inducible kinase 1)
Sus scrofa (pig) : SIK1 (salt inducible kinase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02010,670,747 - 10,680,279 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02012,845,508 - 12,855,040 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42010,282,203 - 10,291,735 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12010,280,420 - 10,292,014 (-)NCBI
Celera2011,458,458 - 11,467,962 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Sik1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 69407
Created: 2001-11-27
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.