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Gene: Akap6 (A-kinase anchoring protein 6) Rattus norvegicus
Symbol: Akap6
Name: A-kinase anchoring protein 6
CRRD ID: 69412
Description: Exhibits several functions, including enzyme binding activity; ion channel binding activity; and protein kinase A regulatory subunit binding activity. Involved in several processes, including positive regulation of cellular protein metabolic process; regulation of intracellular signal transduction; and regulation of muscle system process. Localizes to several cellular components, including T-tubule; intercalated disc; and junctional sarcoplasmic reticulum membrane. Colocalizes with nuclear envelope. Human ortholog(s) of this gene implicated in anorexia nervosa and ovary epithelial cancer. Orthologous to human AKAP6 (A-kinase anchoring protein 6); PARTICIPATES IN protein kinase A (PKA) signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; acrylamide.
Type: protein-coding
Also known as: A kinase (PRKA) anchor protein 6; A-kinase anchor protein; A-kinase anchor protein 6; AKAP-6; mAkap; PRKA6; protein kinase A-anchoring protein 6
Homo sapiens (human) : AKAP6 (A-kinase anchoring protein 6)  HGNC  Alliance
Mus musculus (house mouse) : Akap6 (A kinase (PRKA) anchor protein 6)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Akap6 (A-kinase anchoring protein 6)
Pan paniscus (bonobo/pygmy chimpanzee) : AKAP6 (A-kinase anchoring protein 6)
Canis lupus familiaris (dog) : AKAP6 (A-kinase anchoring protein 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Akap6 (A-kinase anchoring protein 6)
Sus scrofa (pig) : AKAP6 (A-kinase anchoring protein 6)
Chlorocebus sabaeus (African green monkey) : AKAP6 (A-kinase anchoring protein 6)
Heterocephalus glaber (naked mole-rat) : Akap6 (A-kinase anchoring protein 6)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0673,553,111 - 73,991,992 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl673,553,210 - 73,990,534 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0683,111,409 - 83,547,031 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4673,010,779 - 73,354,520 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1673,016,484 - 73,357,646 (+)NCBI
Celera669,046,483 - 69,480,156 (+)NCBICelera
Cytogenetic Map6q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Akap6
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 69412
Created: 2001-11-27
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.