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Gene: Cygb (cytoglobin) Rattus norvegicus
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Symbol: Cygb
Name: cytoglobin
Description: Exhibits catalase activity; fatty acid peroxidase activity; and heme binding activity. Involved in several processes, including negative regulation of collagen biosynthetic process; negative regulation of fibroblast migration; and negative regulation of hepatic stellate cell activation. Localizes to cytoplasm. Used to study liver cirrhosis and renal fibrosis. Biomarker of kidney disease and liver cirrhosis. Orthologous to human CYGB (cytoglobin); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 17beta-estradiol 3-benzoate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Glnf; globin f; HGb; histoglobin; MGC95105; Staap; Stap; stellate cell activation associated protein; stellate cell activation-associated protein
Orthologs:
Homo sapiens (human) : CYGB (cytoglobin)  HGNC  Alliance
Mus musculus (house mouse) : Cygb (cytoglobin)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cygb (cytoglobin)
Pan paniscus (bonobo/pygmy chimpanzee) : CYGB (cytoglobin)
Canis lupus familiaris (dog) : CYGB (cytoglobin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cygb (cytoglobin)
Sus scrofa (pig) : CYGB (cytoglobin)
Chlorocebus sabaeus (African green monkey) : CYGB (cytoglobin)
Heterocephalus glaber (naked mole-rat) : Cygb (cytoglobin)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.010105,618,325 - 105,628,091 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10105,618,326 - 105,628,091 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010105,280,904 - 105,290,670 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410106,759,885 - 106,769,651 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.110106,774,389 - 106,784,155 (-)NCBI
Celera10100,448,536 - 100,458,302 (-)NCBICelera
Cytogenetic Map10q32.2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cygb
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 69415
Created: 2001-11-27
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.