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Gene: Cox4i2 (cytochrome c oxidase subunit 4i2) Rattus norvegicus
Symbol: Cox4i2
Name: cytochrome c oxidase subunit 4i2
CRRD ID: 69422
Description: Predicted to have cytochrome-c oxidase activity. Involved in cellular response to hypoxia. Predicted to localize to mitochondrial respiratory chain complex IV. Orthologous to human COX4I2 (cytochrome c oxidase subunit 4I2); PARTICIPATES IN Alzheimer's disease pathway; Huntington's disease pathway; oxidative phosphorylation pathway; INTERACTS WITH 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine; 2,2',4,4'-Tetrabromodiphenyl ether; ammonium chloride.
Type: protein-coding
Also known as: COX IV-2; Cox4b; CoxIV-2; cytochrome c oxidase subunit 4 isoform 2, mitochondrial; cytochrome c oxidase subunit IV; cytochrome c oxidase subunit IV isoform 2; cytochrome c oxidase subunit IV isoform 2 (lung); cytochrome c oxidase subunit IV isoform 2 precursor; cytochrome c oxidase subunit IVb; cytochrome c oxidase, subunit 4b; cytochrome c oxidase, subunit IVb
Homo sapiens (human) : COX4I2 (cytochrome c oxidase subunit 4I2)  HGNC  Alliance
Mus musculus (house mouse) : Cox4i2 (cytochrome c oxidase subunit 4I2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : LOC102018506 (cytochrome c oxidase subunit 4 isoform 2, mitochondrial)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100980404 (cytochrome c oxidase subunit 4 isoform 2, mitochondrial)
Canis lupus familiaris (dog) : COX4I2 (cytochrome c oxidase subunit 4I2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101956526 (cytochrome c oxidase subunit 4 isoform 2, mitochondrial)
Sus scrofa (pig) : COX4I2 (cytochrome c oxidase subunit 4I2)
Chlorocebus sabaeus (African green monkey) : COX4I2 (cytochrome c oxidase subunit 4I2)
Heterocephalus glaber (naked mole-rat) : LOC101714003 (cytochrome c oxidase subunit 4 isoform 2, mitochondrial)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.03148,234,546 - 148,245,424 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3148,234,193 - 148,245,416 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03154,637,397 - 154,648,541 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43143,103,348 - 143,114,236 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13143,008,969 - 143,019,858 (+)NCBI
Celera3139,977,862 - 139,988,751 (+)NCBICelera
Cytogenetic Map3q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Cox4i2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 69422
Created: 2001-11-27
Species: Rattus norvegicus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.