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Gene: Pdk1 (pyruvate dehydrogenase kinase 1) Rattus norvegicus
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Symbol: Pdk1
Name: pyruvate dehydrogenase kinase 1
Description: Exhibits several functions, including ATP binding activity; protein heterodimerization activity; and protein kinase activity. Involved in cell surface receptor signaling pathway and peptidyl-serine phosphorylation. Localizes to the pyruvate dehydrogenase complex. Orthologous to human PDK1 (pyruvate dehydrogenase kinase 1); PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; Fc epsilon receptor mediated signaling pathway; pyruvate metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial; [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial; MGC108625; PDH kinase 1; PDK p48; pyruvate dehydrogenase kinase isoenzyme 1; pyruvate dehydrogenase kinase, isoenzyme 1; pyruvate dehydrogenase kinase, isozyme 1
Orthologs:
Homo sapiens (human) : PDK1 (pyruvate dehydrogenase kinase 1)  HGNC  Alliance
Mus musculus (house mouse) : Pdk1 (pyruvate dehydrogenase kinase, isoenzyme 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pdk1 (pyruvate dehydrogenase kinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PDK1 (pyruvate dehydrogenase kinase 1)
Canis lupus familiaris (dog) : PDK1 (pyruvate dehydrogenase kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pdk1 (pyruvate dehydrogenase kinase 1)
Sus scrofa (pig) : PDK1 (pyruvate dehydrogenase kinase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0358,530,870 - 58,561,494 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl358,530,870 - 58,558,027 (+)Ensembl
Rnor_5.0365,019,116 - 65,049,739 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4354,292,076 - 54,319,242 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1354,188,447 - 54,215,612 (+)NCBI
Celera356,248,990 - 56,275,768 (+)NCBICelera
Cytogenetic Map3q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Pdk1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 69427
Created: 2001-11-27
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.