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Gene: Synj1 (synaptojanin 1) Rattus norvegicus
Symbol: Synj1
Name: synaptojanin 1
Description: Exhibits phosphatase activity; protein C-terminus binding activity; and protein domain specific binding activity. Involved in several processes, including nervous system development; positive regulation of receptor-mediated endocytosis; and response to retinoic acid. Localizes to several cellular components, including clathrin coat of coated pit; parallel fiber to Purkinje cell synapse; and synaptic membrane. Colocalizes with microtubule. Human ortholog(s) of this gene implicated in Parkinson's disease; Parkinson's disease 20; and early infantile epileptic encephalopathy 53. Orthologous to human SYNJ1 (synaptojanin 1); PARTICIPATES IN altered clathrin-dependent synaptic vesicle endocytosis; clathrin-dependent synaptic vesicle endocytosis; ephrin - ephrin receptor bidirectional signaling axis; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
Also known as: synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1; synaptic inositol-1,4,5-trisphosphate 5-phosphatase 1; synaptojanin-1
Homo sapiens (human) : SYNJ1 (synaptojanin 1)  HGNC  Alliance
Mus musculus (house mouse) : Synj1 (synaptojanin 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Synj1 (synaptojanin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SYNJ1 (synaptojanin 1)
Canis lupus familiaris (dog) : SYNJ1 (synaptojanin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Synj1 (synaptojanin 1)
Sus scrofa (pig) : SYNJ1 (synaptojanin 1)
Chlorocebus sabaeus (African green monkey) : SYNJ1 (synaptojanin 1)
Heterocephalus glaber (naked mole-rat) : Synj1 (synaptojanin 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01131,105,784 - 31,181,573 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1131,104,787 - 31,180,642 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01134,717,258 - 34,792,366 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41130,921,834 - 30,998,609 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11130,921,975 - 30,966,053 (-)NCBI
Celera1129,860,879 - 29,935,097 (-)NCBICelera
Cytogenetic Map11q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Synj1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 69434
Created: 2001-11-27
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.