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Gene: LCN2 (lipocalin 2) Homo sapiens
Symbol: LCN2
Name: lipocalin 2
CRRD ID: 69453
Description: Exhibits enterobactin binding activity; identical protein binding activity; and iron ion binding activity. Involved in defense response to bacterium and sequestering of iron ion. Localizes to extracellular space. Biomarker of COVID-19; essential hypertension; hydronephrosis; hyperuricemia; and kidney disease (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 24p3; 25 kDa alpha-2-microglobulin-related subunit of MMP-9; lipocalin-2; migration-stimulating factor inhibitor; MSFI; neutrophil gelatinase-associated lipocalin; NGAL; oncogene 24p3; p25; siderocalin; siderocalin LCN2
Mus musculus (house mouse) : Lcn2 (lipocalin 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Lcn2 (lipocalin 2)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : LCN2 (lipocalin 2)
Canis lupus familiaris (dog) : LCN2 (lipocalin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lcn2 (lipocalin 2)
Sus scrofa (pig) : LCN2 (lipocalin 2)
Chlorocebus sabaeus (African green monkey) : LCN2 (lipocalin 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl9128,149,071 - 128,153,453 (+)EnsemblGRCh38hg38GRCh38
GRCh389128,149,453 - 128,153,453 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh379130,911,732 - 130,915,734 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369129,951,553 - 129,955,555 (+)NCBINCBI36hg18NCBI36
Build 349127,991,271 - 127,995,288NCBI
Celera9101,562,624 - 101,566,626 (+)NCBI
Cytogenetic Map9q34.11NCBI
HuRef9100,525,402 - 100,529,404 (+)NCBIHuRef
CHM1_19131,062,719 - 131,066,744 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on LCN2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 69453
Created: 2001-11-27
Species: Homo sapiens
Last Modified: 2020-11-03
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.