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Gene: LCN2 (lipocalin 2) Homo sapiens
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Symbol: LCN2
Name: lipocalin 2
Description: Exhibits enterobactin binding activity and iron ion binding activity. Involved in defense response to bacterium and sequestering of iron ion. Localizes to the extracellular space. Biomarker of essential hypertension; hydronephrosis; hyperuricemia; and kidney disease (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 24p3; 25 kDa alpha-2-microglobulin-related subunit of MMP-9; lipocalin-2; migration-stimulating factor inhibitor; MSFI; neutrophil gelatinase-associated lipocalin; NGAL; oncogene 24p3; p25; siderocalin; siderocalin LCN2
Orthologs:
Mus musculus (house mouse) : Lcn2 (lipocalin 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Lcn2 (lipocalin 2)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : LCN2 (lipocalin 2)
Canis lupus familiaris (dog) : LCN2 (lipocalin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lcn2 (lipocalin 2)
Sus scrofa (pig) : LCN2 (lipocalin 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389128,149,453 - 128,153,453 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh379130,911,732 - 130,915,734 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369129,951,553 - 129,955,555 (+)NCBINCBI36hg18NCBI36
Build 349127,991,271 - 127,995,288NCBI
Celera9101,562,624 - 101,566,626 (+)NCBI
Cytogenetic Map9q34.11NCBI
HuRef9100,525,402 - 100,529,404 (+)NCBIHuRef
CHM1_19131,062,719 - 131,066,744 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on LCN2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 69453
Created: 2001-11-27
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.