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Gene: Pdk2 (pyruvate dehydrogenase kinase, isoenzyme 2) Mus musculus
Symbol: Pdk2
Name: pyruvate dehydrogenase kinase, isoenzyme 2
Description: Exhibits pyruvate dehydrogenase (acetyl-transferring) kinase activity. Involved in several processes, including insulin receptor signaling pathway; regulation of acetyl-CoA biosynthetic process from pyruvate; and regulation of gluconeogenesis. Localizes to mitochondrial pyruvate dehydrogenase complex. Orthologous to human PDK2 (pyruvate dehydrogenase kinase 2); PARTICIPATES IN pyruvate metabolic pathway; INTERACTS WITH 1,1-dichloroethene; 1,2-dichloroethane; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial; [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial; PDH kinase 2; pyruvate dehydrogenase 2; pyruvate dehydrogenase kinase, isozyme 2
Homo sapiens (human) : PDK2 (pyruvate dehydrogenase kinase 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pdk2 (pyruvate dehydrogenase kinase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pdk2 (pyruvate dehydrogenase kinase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PDK2 (pyruvate dehydrogenase kinase 2)
Canis lupus familiaris (dog) : PDK2 (pyruvate dehydrogenase kinase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pdk2 (pyruvate dehydrogenase kinase 2)
Sus scrofa (pig) : PDK2 (pyruvate dehydrogenase kinase 2)
Chlorocebus sabaeus (African green monkey) : PDK2 (pyruvate dehydrogenase kinase 2)
Heterocephalus glaber (naked mole-rat) : Pdk2 (pyruvate dehydrogenase kinase 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1195,026,258 - 95,041,354 (-)EnsemblGRCm38mm10GRCm38
GRCm381195,026,258 - 95,041,371 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371194,887,572 - 94,902,685 (-)NCBIGRCm37mm9NCBIm37
MGSCv361194,842,348 - 94,862,996 (-)NCBImm8
Celera11104,636,649 - 104,651,762 (-)NCBICelera
Cytogenetic Map11DNCBI
cM Map1159.01NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Pdk2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 69482
Created: 2001-11-27
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.