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Gene: STX1A (syntaxin 1A) Homo sapiens
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Symbol: STX1A
Name: syntaxin 1A
Description: Exhibits chloride channel inhibitor activity; identical protein binding activity; and kinase binding activity. Involved in protein sumoylation; synaptic vesicle endocytosis; and synaptic vesicle exocytosis. Localizes to the SNARE complex; neuron projection; and plasma membrane. Predicted to colocalize with the voltage-gated potassium channel complex. Implicated in Creutzfeldt-Jakob disease and Hirschsprung's disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: HPC-1; neuron-specific antigen HPC-1; P35-1; STX1; SYN1A; syntaxin 1A (brain); syntaxin-1A
Orthologs:
Mus musculus (house mouse) : Stx1a (syntaxin 1A (brain))  MGI  Alliance
Rattus norvegicus (Norway rat) : Stx1a (syntaxin 1A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Stx1a (syntaxin 1A)
Pan paniscus (bonobo/pygmy chimpanzee) : STX1A (syntaxin 1A)
Canis lupus familiaris (dog) : STX1A (syntaxin 1A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Stx1a (syntaxin 1A)
Sus scrofa (pig) : STX1A (syntaxin 1A)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38773,699,210 - 73,719,673 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37773,113,535 - 73,134,032 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36772,751,476 - 72,771,924 (-)NCBINCBI36hg18NCBI36
Build 34772,558,190 - 72,578,613NCBI
Celera768,591,739 - 68,612,223 (-)NCBI
Cytogenetic Map7q11.23NCBI
HuRef768,995,950 - 69,016,432 (-)NCBIHuRef
CHM1_1773,259,272 - 73,279,754 (-)NCBICHM1_1
CRA_TCAGchr7v2772,446,607 - 72,467,089 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on STX1A
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 69485
Created: 2001-11-27
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.