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Gene: CCN4 (cellular communication network factor 4) Homo sapiens
Symbol: CCN4
Name: cellular communication network factor 4
Description: Predicted to have heparin binding activity and integrin binding activity. Involved in positive regulation of inflammatory response; positive regulation of osteoblast differentiation; and regulation of cytokine secretion. Localizes to cytosol and extracellular space.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CCN family member 4; CTC-458A3.8; FLJ14388; WISP-1; WISP1; WISP1 3'UTR-associated RNA 1; WISP1 overlapping transcript 1; WISP1 overlapping transcript 1 (non-protein coding); WISP1-OT1; WISP1-UT1; WISP1c; WISP1i; WISP1tc; Wnt-1 inducible signaling pathway protein 1; wnt-1 signaling pathway protein 1; wnt-1-induced secreted protein; WNT1 induced secreted protein 1; WNT1 inducible signaling pathway protein 1; WNT1-inducible-signaling pathway protein 1
Mus musculus (house mouse) : Ccn4 (cellular communication network factor 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ccn4 (cellular communication network factor 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ccn4 (cellular communication network factor 4)
Pan paniscus (bonobo/pygmy chimpanzee) : CCN4 (cellular communication network factor 4)
Canis lupus familiaris (dog) : CCN4 (cellular communication network factor 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ccn4 (cellular communication network factor 4)
Sus scrofa (pig) : CCN4 (cellular communication network factor 4)
Chlorocebus sabaeus (African green monkey) : CCN4 (cellular communication network factor 4)
Heterocephalus glaber (naked mole-rat) : Ccn4 (cellular communication network factor 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl8133,191,039 - 133,231,690 (+)EnsemblGRCh38hg38GRCh38
GRCh388133,190,907 - 133,231,690 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh378134,203,282 - 134,243,933 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 368134,272,494 - 134,310,753 (+)NCBINCBI36hg18NCBI36
Build 348134,272,493 - 134,309,234NCBI
Celera8130,380,567 - 130,419,496 (+)NCBI
Cytogenetic Map8q24.22NCBI
HuRef8129,522,987 - 129,563,677 (+)NCBIHuRef
CHM1_18134,244,050 - 134,284,955 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on CCN4
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 69487
Created: 2001-11-27
Species: Homo sapiens
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.